Neurally Adjusted Ventilatory Assist for Weaning From Invasive Mechanical Ventilation in Critically Ill Children

Chulalongkorn University

Status: Not yet enrolling

Conditions: Neurally Adjusted Ventilatory Assist; Critically Ill; Mechanical Ventilator Weaning; Mechanical Ventilation

Treatments: Procedure: NAVA

Study type: Interventional

Funder types: Other

Identifiers

NCT06157593

24112566

Details and patient eligibility

About

The goal of this clinical trial is to compare weaning from mechanical ventilation in critically ill children. The main questions it aims to answer are:

• Will weaning with neurally adjusted ventilatory assist (NAVA) mode ventilation result in shorter ventilator day than synchronised intermittent mandatory ventilation (SIMV) mode?
• Will weaning with NAVA mode ventilation result in shorter paediatric intensive care unit (PICU) length of stay than SIMV mode? Participants will be randomised to NAVA or SIMV group for weaning from mechanical ventilation, then PICU outcomes from both groups will be collected, analysed and compared.

Enrollment: 60 estimated patients

Sex: All

Ages: 1 month to 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• all critically ill children admitted to PICU

Exclusion criteria

• failure to obtain informed consent

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

NAVA

Experimental group

Treatment:

Procedure: NAVA

SIMV

No Intervention group