Neuro-ophthalmology and Autoimmune Encephalitis (NODE)

Civil Hospices of Lyon

Status: Completed

Conditions: Autoimmune Encephalitis

Treatments: Other: oculomotor movement recordings, neurovisual assessment

Study type: Observational

Funder types: Other

Identifiers

NCT03872284

2019-A00684-53 (Other Identifier)

69HCL18_0749

Details and patient eligibility

About

Autoimmune encephalitis represents a group of rare and heterogeneous neurological disorders. Pathophysiological mechanisms in these diseases are still unknown. Recently, oculomotor and neurovisual disorders have been described. Cerebral areas and neuronal networks associated with these abnormalities are well described. The investigator proposes to study and describe such neuro-ophthalmological disorders in a prospective cohort of patients with a autoimmune encephalitis, to better understand the pathophysiological basis of this neurological condition.

Enrollment: 2 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of autoimmune encephalitis
• With or without pathological antibody
• Aged from 18 to 70 years old
• Able to understand the aims and methods of this project
• Non opposed to the participation of this study

Exclusion criteria

• Other neurological, psychiatric or systemic conditions, which could induce neuro-ophthalmological signs Cognitive impairment, which is not linked to autoimmune encephalitis
• Ophthalmological condition, which could modify the interpretation of neuro-ophthalmological data Inability to remain seated
• Pregnancy or breast feeding
• Adults under guardianship

Trial design

2 participants in 1 patient group

1

Description:

Patients in the study group have a diagnosis of autoimmune encephalitis, are 18 to 70 years old, and have no significant comorbidity such as psychiatric, neurological conditions and able to understand the aim of this study.

Treatment:

Other: oculomotor movement recordings, neurovisual assessment