Neuro-urological Outcome After Spinal Cord Injury

Balgrist University Hospital

Status: Completed

Conditions: Urinary Bladder Neurogenic Dysfunction

Treatments: Other: Video-urodynamic examination

Study type: Observational

Funder types: Other

Identifiers

NCT01297660

KEK-2010-0207/01

Details and patient eligibility

About

Most patients with spinal cord injury suffer from bladder dysfunction which may - especially in the long-term - impair renal function. Improved treatment during the last decades improved life expectancy and quality of life. This study evaluates the bladder function in the long-term after spinal cord injury.

Full description

Bladder dysfunction is a common consequence of spinal cord injury and depends on the completeness and the level of the lesion. Patients with suprasacral injury usually suffer from neurogenic detrusor overactivity mostly combined with detrusor sphincter dyssynergia. Without adequate treatment, this adverse combination puts the upper urinary tract at risk due to high intravesical pressure often causing vesico-ureteral reflux. Based on improved therapeutic options in the last decades, life expectancy and quality of life constantly increased in spinal cord injury patients. The investigators aim to evaluate the bladder function in the long-term after spinal cord injury.

Enrollment: 55 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Spinal cord injury for at least 5 years
• Neurogenic lower urinary tract dysfunction
• Written informed consent

Exclusion criteria

• Lower urinary tract dysfunction due to other causes than spinal cord injury

Trial design

55 participants in 1 patient group

patients with SCI for at least 5 years

Description:

Ages Eligibility: minimum 18 years Genders Eligibility: female and male

Treatment:

Other: Video-urodynamic examination