Neurobehavioral Mechanisms of Moral Reasoning: an EEG Study in Patients With Borderline Personality Disorder

Charité University Medicine Berlin

Status: Completed

Conditions: Borderline Personality Disorder (BPD)

Study type: Observational

Funder types: Other

Identifiers

NCT07091409

BDP-MoDe

Details and patient eligibility

About

We will investigate social cognition in patients with Borderline personality disorder (BPD) combined with electroencephalographic (EEG) measures.

Full description

We will investigate whether patients with Borderline personality disorder (BPD) show a negativity bias in evaluating social situations.

We will also asses emotional arousal, theory of mind (ToM) abilities, and inhibitory control in patients with BPD.

In addition to behavioral outcome variables, electroencephalographic (EEG) measures will be recorded. Healthy controls server as a control group.

Enrollment: 64 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

BPD diagnosis BMI between 17.5 and 30 acute major depressive episode, psychotic symptoms, substance addiction or acute suicidal behavior

Exclusion criteria

neurological, metabolic, endocrine, autoimmune and CNS diseases, any other severe somatic diseases, and pregnancy or breastfeeding during the last 12 months

Trial design

64 participants in 2 patient groups

Patients with BPD

Healthy individuals