Neurocognitive Dysfunction After Anesthesia in Patients With Recent Concussion

Mayo Clinic

Status: Completed

Conditions: Concussion, Brain

Treatments: Other: Neurocognitive Testing

Study type: Interventional

Funder types: Other

Identifiers

NCT03952208

18-006578

Details and patient eligibility

About

Researchers are trying to determine if the impact of a concussion on the brain is affected by anesthesia and surgery.

Full description

All subjects will complete pre and post procedure assessments prior to undergoing a planned surgery/anesthetic standard of care.

Enrollment: 52 patients

Sex: All

Ages: 16+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male or Female >16 years of age with a recent concussion (<10 weeks) from planned procedure under anesthesia.

Exclusion criteria

• Neurologic history including history of severe cognitive disease, disorder, or delay, attention disorder, moderate to severe TBI history, neurovascular order or trauma.

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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52 participants in 2 patient groups

Concussion Group

Experimental group

Description:

Subjects diagnosed with concussion defined as a clinician-diagnosed disease by the International Classification of Diseases (ICD)-10 due to a head injury with a Glasgow Coma Score ≥13 undergoing a planned surgery/anesthetic standard of care will undergo neurocognitive testing pre and post surgery/anesthetic.

Treatment:

Other: Neurocognitive Testing

Matched Subjects Group

Experimental group

Description:

Matched subjects without concussion undergoing a planned surgery/anesthetic standard of care, matching for procedural type, sex, age ± 2 years, and adherence to the exclusion criteria will undergo neurocognitive testing pre and post surgery/anesthetic.

Treatment:

Other: Neurocognitive Testing