Neurocognitive Functions of Recovered COVID-19 Patients

National Institute on Drug Dependence, China

Status

Unknown

Conditions

Covid-19

Cognition

Treatments

Behavioral: Trier Social Stress Test

Study type

Observational

Funder types

Other

Identifiers

NCT04622748

NIDD-2020-Neurocognition

Details and patient eligibility

About

This study is carried on in Wuchang Hospital in Wuhan, China. The investigators plan to recruit 80 patients with COVID-19 and 80 matched healthy control. Using the design of case-control study, the study aims to assess the neurocognitive functions such as executive function and attentional bias in recovered patients with COVID-19 under normal and stress conditions, and to analyze the influencing factors of neurocognitive functions, such as mental health conditions, inflammation indicators and cardiopulmonary function.

Enrollment

160 estimated patients

Sex

All

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Recovered COVID-19 patients or uninfected residents in Wuhan, with an education level above elementary school and are able to complete cognitive tasks;
Willing to participate in this study and sign informed consent.

Exclusion criteria

Subjects with body temperature> 38°C;
Subjects who are in menstruation and pregnancy;
Subjects suffering from cardiopulmonary diseases before the new coronary pneumonia epidemic (such as heart disease, pulmonary hypertension, congestive heart failure, etc.);
Subjects with severe disturbances in consciousness, cognitive dysfunction, mental disorders, visual and hearing disorders, bone and joint diseases, etc.;
Subjects with abnormal immune system and severe organ dysfunction (heart, liver, kidney, etc.);
Subjects who are unwilling to participate in this study and cannot complete all surveys and cognitive function tests.