Neurodevelopmental Disorders in Children With Congenital Heart Disease (NeuroDis-CHD)

University Hospital, Lille

Status: Completed

Conditions: Congenital Heart Disease

Treatments: Other: Ages & Stages Questionnaires, Third Edition in French (ASQ-3™)

Study type: Observational

Funder types: Other

Identifiers

NCT03360370

2017_31

2017-A01839-44. (Other Identifier)

Details and patient eligibility

About

Children with congenital heart disease are at risk for neurodevelopmental disorders, these disorders impacting their quality of life and their integration into society.

The aim of this study is to detect neurodevelopmental disorders in children (aged from 6 to 66 months) with congenital heart disease in Nord-Pas-De-Calais (France) and to evaluate the frequency and risk factors of these neurodevelopmental disorders for a better follow-up.

This study will help implementing a specific program for the evaluation and management of neurodevelopmental disorders in children suffering from congenital heart disease in Nord-Pas-De-Calais and more globally, in the region Hauts-De-France.

Full description

Are selected children with "significant" congenital heart disease (aged from 6 to 66 months) in "Nord-Pas-De-Calais" fulfilling inclusion criteria. A reliable and valid questionnaire used to screen developmental delays of children aged from one month to 66 months is completed by volunteer parents at the time of the study. Data of the questionnaire is collected and a scoring by professional is provided ; children at risk for neurodevelopmental delays are depicted.

In parallel, medical and surgical history is also collected to detect risk factors for neurodevelopmental disorders.

The frequency of neurodevelopmental disorders in this screened population according to risk factors (among neonatal data, severity of congenital heart disease, surgery, length of stay at hospital,... ) will be evaluated. The ratio children with neurodevelopmental disorders for whom specific care was implemented/ children with neurodevelopmental disorders who did not have specific care despite neurodevelopmental disorders will be established.

Follow-up action will be taken for children at risk for developping neurological disorders highlighted by the screening.

This study will help implementing a specific program for evaluation and management of neurodevelopmental disorders for children with congenital heart disease in our region.

Enrollment: 233 patients

Sex: All

Ages: 6 to 66 months old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children aged 6 to 66 months at the time of study
• living in region "Nord-Pas-De-Calais"
• with " significant" congenital heart disease (= complex congenital heart diseases operated or not, simple or moderate congenital heart disease who had cardiac surgery)
• Followed by the Pediatric Cardiology Department of Lille University Hospital, or patients having a cardiopediatric follow-up outside Lille University Hospital but having been taken in charge at the University Hospital of Lille for any reason (cardiac or not)

Exclusion criteria

Children :

• lost to sight
• Deceased
• with congenital heart disease, living in Nord-Pas-de-Calais but never having been taken in charge at Lille University Hospital
• with mild or moderate congenital heart disease not having undergone surgery or having only undergone cardiac catheterization
• with cardiac surgery not performed in the Centers of Jacques CARTIER and Marie LANNNELONGUE

Trial design

233 participants in 1 patient group

6 to 66 months children with significant CHD

Description:

Children with "significant" congenital heart disease (CHD) aged from 6 to 66 months at the time of the study and fulfilling inclusion criteria for whom an age-appropriate questionnaire completed by parents (Ages \& Stages Questionnaires, Third Edition in French (ASQ-3™) will be used to screen developmental delays.

Treatment:

Other: Ages & Stages Questionnaires, Third Edition in French (ASQ-3™)