Neurodynamic Interventions for Multiple Sclerosis

Universidad Rey Juan Carlos

Status: Completed

Conditions: Multiple Sclerosis

Treatments: Other: Physical Therapy; Other: Physical Therapy plus Neurodynamic

Study type: Interventional

Funder types: Other

Identifiers

NCT03595631

PI-URJC 572

Details and patient eligibility

About

A randomized, parallel-group, clinical trial will be conducted to compare the immediate effects of the inclusion of a neurodynamic intervention into a multimodal physiotherapy program on pressure pain sensitivity, pain and manual dexterity in patients with multiple sclerosis

Enrollment: 32 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• a diagnosis of multiple sclerosis according to the modified McDonald criteria;
• symptoms of paresthesia and lack of sensitivity in the upper extremity;
• Expanded Disability Status Scale (EDSS) between 0 and 6.5 points;
• absence of cognitive deficit.

Exclusion criteria

• any exacerbation of multiple sclerosis during the previous 3 months;
• previous hand surgery or steroid injections treatment in the upper extremity;
• multiple diagnoses on the upper extremity (e.g., cervical radiculopathy);
• cervical, shoulder, or upper extremity trauma;
• other comorbid musculoskeletal medical conditions;
• mini-mental state examination <25

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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32 participants in 2 patient groups

Physical Therapy

Active Comparator group

Description:

Patients will receive 5 session of multimodal physiotherapy treatment of 30min duration including low-load strength exercises, soft tissue mobilization and muscle-tendon stretching exercises twice per week.

Treatment:

Other: Physical Therapy

Physical Therapy plus neurodynamic

Experimental group

Description:

Patients will receive 5 session of multimodal physiotherapy treatment of 30min duration including low-load strength exercises, soft tissue mobilization and muscle-tendon stretching exercises twice per week. In addition, they will also receive bilateral nerve slider neurodynamic interventions targeting the median, ulnar and radial nerves.

Treatment:

Other: Physical Therapy plus Neurodynamic