Neuroendocrine Dysfunction in Traumatic Brain Injury: Correlation With Cognitive Dysfunction and Repair

Denver Research Institute

Status: Terminated

Conditions: Traumatic Brain Injury

Study type: Observational

Funder types: Other

Identifiers

NCT00336726

GR-735

Details and patient eligibility

About

Traumatic Brain Injury (TBI) is a neurologic disorder cuased by physical trauma to the brain. Neuroendocrine abnormalities in these patients have been reported, including central hypogonadism within hours of the insult and eventual recovery of the hypothalamic-pituitary-gonadal axis with recovery of cognitive function to baseline. This pilot study will measure hormonal level of neuroendocine function at the time of TBI and various time points during recovery.

Sex: Male

Ages: 21 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male subjects having had a recent traumatic brain injury.

Exclusion criteria

• Currently receivng sex steroids, glucocorticoids, or have an inability to complete the neurobehavioral assessment.