Neurofeedback and Working Memory Training for Children and Adolescents With ADHD (KITE)

Karolinska Institute

Status: Completed

Conditions: Attention Deficit Disorder

Treatments: Behavioral: WM training; Behavioral: Live Z-score training; Behavioral: SCP training

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT01841151

KITE

Details and patient eligibility

About

The purpose of this study is to investigate if neurofeedback and working memory training improves core symptoms of ADHD in children and adolescents.

Full description

This study investigates two types of Neurofeedback (NF), one well-established and well-researched protocol called Slow Cortical Potential NF (SCP), and a newer and less researched, yet popular among private clinicians, the so-called live z-score training (LZT). These methods are compared to working memory training (WMT) and a passive control condition, treatment-as-usual only (TAU). The active conditions (SCP/LZT/WMT) are delivered high frequent, with 5 sessions/week, for a total of 25 sessions.

Outcomes measures are taken at Preintervention and Postintervention, as well as at a 6-month follow-up assessment.

Enrollment: 202 patients

Sex: All

Ages: 9 to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical AD/HD diagnose according to DSM-IV-TR and K-SADS interview, 9-17 years old, unmedicated or under stable medication with stimulants or corresponding since at least one month.

Exclusion criteria

• IQ <70 (WISC-IV or WAIS-IV), clinically instable psychiatric state e.g. severe depression, OCD, self-injurious behaviour, bipolar disorder, severe somatic (neurologic) disease, very limited knowledge in the Swedish language.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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202 participants in 4 patient groups

SCP training

Active Comparator group

Description:

Neurofeedback 1 (NF1) Slow Cortical Potential (SCP) training

Treatment:

Behavioral: SCP training

Live Z-score training

Active Comparator group

Description:

Neurofeedback 2 (NF2) Live Z-score training

Treatment:

Behavioral: Live Z-score training

WM training

Active Comparator group

Description:

Working Memory training (WMt)

Treatment:

Behavioral: WM training

Waiting-list

No Intervention group

Description:

Treatment as usual only