Neurofeedback Improves Cognitive Performance and EEG Activity in Elderly With Mild Cognitive Impairment (Neurofeedel)

Fabienne Marlats

Status: Completed

Conditions: Mild Cognitive Impairment

Treatments: Behavioral: SMR neurofeedback training to MCI

Study type: Interventional

Funder types: Other

Identifiers

NCT03855319

LUS3EEGNF

Details and patient eligibility

About

This is a non-pharmacological pilot study showing the improvement of a SMR/theta neurofeedback training program on cognitive performance and EEG activity in Elderly with Mild Cognitive Impairment.

Full description

Neurofeedback training (NF) as self-regulation method of brain activity, may be beneficial in elderly with mild cognitive impairment. In this pilot study, the investigators studied whether a sensorimotor(SMR)/theta NF training could improve cognitive performance and brain electrical activity in a sample group of elderly patients with mild cognitive impairment. Twenty participants performed an electroencephalography recording, a battery of neuropsychological tests before the neurofeedback training program (T0), following the neurofeedback training program (T1) and 1-month follow-up (T2).

Enrollment: 20 patients

Sex: All

Ages: 65 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of Mild Cognitive Impairment
• education level of 9 years of studies minimum
• righthandedness
• subjective memory complaint confirmed by an informant
• a Mini Mental Status Examination score >20.
• preserve activity of daily living and absence of dementia.

Exclusion criteria

• elderly persons who were under guardianship
• resident in nursing facilities
• neurological disease, psychiatric disease
• and involved in another cogniitve intervention.

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

SMR neurofeedback training to MCI

Experimental group

Description:

A sensorimotor/theta neurofeedback training consisted of 20 individuals sessions, twice a week during 11 weeks maximum. For each subject, NF was planned and conducted by a neuropsychologist experienced in neurophysiology an neurofeedback. Each session lasted 1h10 minutes and was conducted as follows: * Preparation and installation of the electrodes, verification of the impedance, adjustement of the calibration. * NF training (tasks and video described below)(45minutes) * Feedback and debriefing about the session (15 minutes)

Treatment:

Behavioral: SMR neurofeedback training to MCI