Neurofeedback Training of Metacognition in Subjects With Alcohol Use Disorder. Disorder Induces Neural Modifications: an Event-related Potentials Study

CHU Brugmann University Hospital

Status: Enrolling

Conditions: Alcohol Use Disorder

Treatments: Device: Neurofeedback active; Device: Neurofeedback placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT05913518

Neurofeedback

Details and patient eligibility

About

Addressing cognitive deficits in alcohol use disorder (AUD) supports recovery. Impaired metacognitive functioning in AUD causes compromised recognition of the interoceptive state leading to the maintenance of alcohol abuse despite negative consequences. By promoting greater self-awareness and self-regulation, neurofeedback training is of high relevance in metacognition remediation to support abstinence.

The main objective of the present study is to validate neurofeedback as a complementary clinical tool to overcome metacognitive deficits that represent a significant factor in the maintenance of harmful consumption behavior and relapse phenomena in AUD.

Enrollment: 130 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged between 18 and 65 years old undergoing a 3- to 4-week detoxification treatment program at the Alcohol Unit of CHU Brugmann hospital (Brussels, BELGIUM), who have been diagnosed with severe AUD (alcohol use disorder) according to the DSM-V-TR.

Exclusion criteria

• history of neurological disorders
• other serious medical conditions
• neuroleptic treatment are excluded.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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130 participants in 3 patient groups, including a placebo group

Active neurofeedback group

Experimental group

Treatment:

Device: Neurofeedback active

Placebo feedback group

Placebo Comparator group

Treatment:

Device: Neurofeedback placebo

Control group

No Intervention group