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Neuroimaging Findings in Patients With COVID-19

S

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Status

Completed

Conditions

COVID-19
Neuroimaging

Treatments

Diagnostic Test: Neuroimaging Findings in Patients With COVID-19

Study type

Observational

Funder types

Other

Identifiers

NCT04734223
09.25.2020/587

Details and patient eligibility

About

This study aimed to discuss the neuroimaging findings and indications, epidemiological data, laboratory values, and the relationship of these variables with mortality in patients with COVID-19.

Full description

COVID-19 can present as neurological symptoms such as anosmia, headache, taste perversion, dizziness, syncope, and altered state of consciousness. It has been reported in previous studies that thromboembolic ischemic and hemorrhagic strokes associated with COVID-19 have been observed in the early period. It has been suggested that conditions characterized by neurological sequelae, such as encephalitis and encephalopathy, ataxic seizures, Guillain-Barré syndrome (GBS), demyelinating diseases, and neuromuscular disorders may occur in the longer term.In the present study, the investigators aimed to reveal the findings of neuroimaging analyses performed in patients followed up with a diagnosis of COVID-19 who had neurological symptoms, discuss the relationship of these findings with laboratory and epidemiological data, and emphasize that CNS involvement in these patients should not be overlooked. In this study, 436 patients with COVID-19 who underwent at least one neuroimaging procedure during April 2020-December 2020 due to neurological symptoms and whose diagnosis was confirmed by reverse transcriptase-polymerase chain reaction test were included. Although computed tomography was predominantly used for imaging, magnetic resonance imaging was also used when necessary. The patients were grouped based on imaging findings, and statistical evaluations were made between the groups.

Enrollment

436 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • COVID-19 RT-PCR positivity-
  • older than 18 years old

Exclusion criteria

  • younger than 18 years old

Trial design

436 participants in 4 patient groups

Group 1
Description:
The first group consisted of 46 patients whose neuroimaging findings demonstrated acute/subacute infarction, bleeding, encephalitis, and venous sinus thrombosis
Treatment:
Diagnostic Test: Neuroimaging Findings in Patients With COVID-19
Group 2
Description:
The 2nd group (N=390) was obtained by subtracting the 1st group from all cases.
Treatment:
Diagnostic Test: Neuroimaging Findings in Patients With COVID-19
Group 3
Description:
The third group (N = 189) consisted of patients of the first group and patients with chronic ischemic changes observed in neuroimaging
Treatment:
Diagnostic Test: Neuroimaging Findings in Patients With COVID-19
Group 4
Description:
The 4th group (N=247) was obtained by subtracting the 3rd group from all cases.
Treatment:
Diagnostic Test: Neuroimaging Findings in Patients With COVID-19

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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