Neurological Fate, Prematurity and Genetic Susceptibility Factors (GENIMOC)

Nantes University Hospital (NUH)

Status: Completed

Conditions: Premature; Infertility of Cervical Origin; Polymorphism, Restriction Fragment Length

Treatments: Other: no intervention

Study type: Observational

Funder types: Other

Identifiers

NCT04298346

RC19_0035

Details and patient eligibility

About

This study could help identify aggravating or protective genetic polymorphisms associated with cerebral palsy. Populations of premature babies at different risk of cerebral palsy could thus be individualized with an impact on their monitoring and on the pathophysiological understanding of the processes leading to neurological lesions.

Enrollment: 27 patients

Sex: All

Ages: 5 to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• children born prematurely at term <34 weeks between 2008 and 2015
• assessed at the age of 2 within the Growing Together Network in Pays de Loire
• parental consent for the collection of data from their child and for intraoral sampling for the search for genetic factors.

Exclusion criteria

• children who died after the age of 2
• children who refused and / or whose parents refused to participate in the study

Trial design

27 participants in 2 patient groups

Case

Treatment:

Other: no intervention

Control

Treatment:

Other: no intervention