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screen for neurologic and psychiatric disorders in children and
adolescents with IBD.
Full description
Neurologic symptoms have a great importance in early diagnosis and
treatment preventing major morbidity and later sequelae, especially if they
precede GI symptoms
The prevalence of neurologic manifestations of IBD varies between 0.2% and
36%. Their pathogenesis of neurologic manifestations in IBD consists of 6
mechanisms: 1.malabsorption and nutritional deficiency 2.metabolic agents
3.infections complicating immune suppression 4.side effects of medications or
iatrogenic as a surgical complication 5.thromboembolism 6.immunological
factors
UC patients are similar to or higher than CD patients in the probability of
neurologic symptoms. Neurologic manifestations and complications include:
headache, dizziness, hypotonia, ADHD, tics, sensory complaints, seizures,
neuropsychiatric disorders, peripherial neuropathy, meningitis, vestibular
dysfunction, idiopathic IC hypertension, cerebral vasculitis, demyelinating
disorders and migraine
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Central trial contact
Bishoy Shehata Faheem, Resident doctor
Data sourced from clinicaltrials.gov
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