Neuromodulation of Motion Illusions (Vection) (NEUROVEC)

Grenoble Alpes University Hospital Center (CHU)

Status

Unknown

Conditions

Healthy

Treatments

Device: electroencephalography

Device: non-invasive neuromodulation

Device: anatomical MRI

Study type

Interventional

Funder types

Other

Identifiers

NCT05198440

ID/RCB 2019-A03159-48

Details and patient eligibility

About

Virtual reality systems or simulators are more and more frequently used in the field of learning but also in motor rehabilitation. One of the key points of the success of these systems is the experience of "presence" which is associated with the capacity of these technologies to develop in the observer, who is static, the sensation of moving in the virtual environment (vection). However, the simulation generates a sensory conflict (an optical flow specifying self-motion and vestibular stimuli specifying body immobility). This conflict influences the temporal characteristics of the vection and consequently modifies the way users act in their virtual environment. Thus, contrary to a real situation, vection does not occur instantaneously with the appearance of a visual movement. Moreover, the visual stimulus often generates alternating periods of perception of movement of the environment and of oneself (bistable perception) which can lead to "simulator sickness", a disabling situation for the user. Thus, as vection is an essential element to allow an "optimal transfer of learning" from the simulator to reality, it may be important to promote its emergence while limiting its bistability.

The aim of this project is to study the inhibitory or facilitative modulation of the emergence of the vection phenomenon by the use of non-invasive cortical stimulation techniques (transcranial electrical stimulation (tES), transcranial alternative current stimulation (tACS), and repeated transcranial magnetic stimulation (rTMS)).

Enrollment

90 estimated patients

Sex

All

Ages

18 to 40 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Healthy subjects aged 18 to 40 years
Right-handed subjects
Signed informed consent,
Medical examination performed prior to participation in the research,
Affiliation to or beneficiary of a social security plan

Exclusion criteria

Contraindications (CI) to the practice of MRI, EEG, TMS & tES
Existence of a severe general condition: cardiac, respiratory, hematological, renal, hepatic, cancerous,
Regular use of anxiolytics, sedatives, antidepressants, neuroleptics,
Characterized psychiatric pathology,
Ingestion of alcohol before the examination,
Pregnant, parturient or breastfeeding women
Person deprived of liberty by judicial or administrative decision, person under a legal protection measure (under guardianship or curators)
Participation in other interventional research protocols in progress with an exclusion period or in the previous week Subject who would receive more than 4500 euros of compensation due to his participation in other research involving the human person in the 12 months preceding this study