Neuromonitoring During Rapid Ventricular Pacing in Patients Undergoing Cerebral Aneurysm Surgery

Antwerp University Hospital (UZA)

Status: Completed

Conditions: Cerebral Arterial Aneurysm; Ventricular Rate Response Pacing

Treatments: Other: rapid ventricular pacing; Procedure: Surgery

Study type: Interventional

Funder types: Other

Identifiers

NCT03185091

12/50/410

Details and patient eligibility

About

To evaluate the effect of rapid ventricular pacing on the oxygenation of the brain in patients scheduled for cerebral aneurysm clipping surgery or arteriovenous malformation surgery.

Full description

Patients scheduled for cerebral aneurysm clipping surgery or arteriovenous malformation surgery(ASA 1to 3 over 18years) receive standard care general anesthesia including central venous line for rapid ventricular pacing technique. A contralateral Foresight sensor is placed on the forehead of the patient at induction. After the craniotomy two micro electrodes(PBtO2 and cerebral blood flow) are placed in the brain and fixated. A subdural strip electrode is placed on the surface of the brain to record the electrical activity. Effect of mild hyperventilation and oxygenation with 100% O2 is evaluated.

Enrollment: 7 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• scheduled for cerebral aneurysm surgery or arterial venous malformation
• American Society of Anesthesiologists classification 1, 2, or 3

Exclusion criteria

• non

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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7 participants in 1 patient group

rapid ventricular pacing

Other group

Description:

Safety of rapid ventricular pacing during neurosurgical procedures

Treatment:

Other: rapid ventricular pacing

Procedure: Surgery