Neuromuscular and Cognitive Fatigue During a 24 Hour Treadmill Running Exercise

Centre Hospitalier Universitaire de Saint Etienne

Status: Completed

Conditions: Healthy

Treatments: Other: no sleeping; Procedure: running during 24 hours without sleep

Study type: Interventional

Funder types: Other

Identifiers

NCT00428779

0601095

DGS 2006-0111

2006-A00312-49

Details and patient eligibility

About

The main purpose of the present study is to determine the relative contributions of central and peripheral fatigue during an ultra-endurance exercise.

Full description

For that purpose, 14 subjects running 24 hours on a treadmill will be compared with a control group being awake during the same period. Subjects who running will have electrically evoked forces on the muscles associated EMG activity, blood samples and muscle biopsy.

Enrollment: 30 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• The subjects of the experimental group will be recruited among experienced ultra-runners . They all have run at least a 12 hour race or longer.
• The control group will be recruited among experienced ultra-runners . Age of control group will be age experimental group more or less 2 years.

Exclusion criteria

• The subjects will not be selected if:

  • they were injured in the 3 months before the experiment
  • they had a tendon or joint pathology that could impair strength measurements.
  • they participate to an other experiment at the same time

Trial design

Primary purpose: Health Services Research

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

30 participants in 2 patient groups, including a placebo group

1

Experimental group

Description:

patients running during 24 hours without sleep

Treatment:

Procedure: running during 24 hours without sleep

2

Placebo Comparator group

Description:

patients without sleep during 24 hours

Treatment:

Other: no sleeping