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Neuromuscular Electrical Stimulation in Pulmonary Arterial Hypertension

D

Dokuz Eylül University (DEU)

Status

Completed

Conditions

Pulmonary Arterial Hypertension

Treatments

Device: Neuromuscular electrical stimulation

Study type

Interventional

Funder types

Other

Identifiers

NCT03612115
2217-GOA

Details and patient eligibility

About

This study aimed to investigate the effects of neuromuscular electrical stimulation on peripheral muscles and other physical and psychosocial variables in patients with pulmonary arterial hypertension. This study was designed as an assessor-blind randomized controlled trial. Thirty-one patients with pulmonary arterial hypertension will be recruited. The participants will randomly divided two parallel groups as treatment and control. For the treatment group, neuromuscular electrical stimulation will be applied to the bilateral deltoid and quadriceps femoris muscles with 50 Hz for 3 days/week, 8 weeks. Control group will not be received any additional treatment, just given healthy life recommendations such as walking. The participants will be assessed before and after the treatment by a blind assessor to the group allocation. The outcome measure will be assessments of the upper and lower limb muscle strength, respiratory muscle strength, muscle cross-sectional area and thickness, pulse wave velocity, exercise capacity, walking speed, functional mobility and balance performances, balance confidence, fatigue perceptions, physical activity level, activities of daily living and quality of life.

Enrollment

31 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Elevated pulmonary artery pressures measured by right heart catheterization
  • New York Heart Association class II or III
  • Stabile Pulmonary Arterial Hypertension-specific pharmaceutical therapy for 3 months

Exclusion criteria

  • Orthopaedic problems
  • Significant restrictive or obstructive pulmonary disease
  • Acute cor pulmonale.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

31 participants in 2 patient groups

Neuromuscular electrical stimulation intervention
Experimental group
Description:
Neuromuscular electrical stimulation treatment
Treatment:
Device: Neuromuscular electrical stimulation
Control
No Intervention group
Description:
No additional intervention

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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