Neuromuscular Electrical Stimulation on Median Nerve Facilitates Low Motor Cortex Excitability in Human With Spinocerebellar Ataxia

Chang Gung University

Status

Completed

Conditions

Spinocerebellar Ataxia

Treatments

Device: Neuromuscular electrical stimulation

Study type

Interventional

Funder types

Other

Identifiers

NCT02103075

91-221

Details and patient eligibility

About

Spinocerebellar ataxia (SCA) is a hereditary disorder with movement incoordination. The ataxia performed low intra-cortical facilitation mainly due to the degenerative cerebellum. Noninvasive sensory stimulations such as peripheral electrical stimulation were reported to modulate the excitability of the motor excitability. Neuromuscular electrical stimulation (NMES) was proposed as a neuromodulation tool for the aberrant motor excitability on the SCA. This study aims to investigate the effect of NMES on the motor excitability in the SCA, and the differentiation on the central or peripheral motor excitability changed by the NMES.

Enrollment

29 patients

Sex

All

Ages

20+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

Clinical diagnosis of Spinocerebellar ataxia
No history of epilepsy
No other neuromuscular disorder
No fracture within the last six months and restricted movement on the upper extremity
Limited trembling hand allowed for the EMG recording.