Neuromuscular Ultrasound in ALS

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Duke University

Status

Completed

Conditions

ALS

Treatments

Other: Ultrasound of nerve and muscle

Study type

Observational

Funder types

Other

Identifiers

NCT01785550
Pro00042025

Details and patient eligibility

About

Amyotrophic Lateral Sclerosis (ALS) is a progressive fatal neurodegenerative disease affecting motor neurons. Early diagnosis is essential for the success of clinical trials and objective biomarkers are needed for monitoring disease progression. Nerve and muscle ultrasound may provide this information. This study will collect pilot data to evaluate the value of muscle and nerve ultrasound to identify and monitor disease progression in ALS.

Enrollment

40 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Subjects referred to the electromyography laboratory for ALS.

Exclusion criteria

  • Patients with known comorbid myopathy or neuropathy will be excluded from the study.
  • Patients unable to provide their own consent will be excluded.

Trial design

40 participants in 2 patient groups

Control Group
Description:
No intervention to be performed.
Ultrasound Group
Description:
All will receive nerve and muscle ultrasound.
Treatment:
Other: Ultrasound of nerve and muscle

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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