Neuropathy Walks (Cross-sectional)

Rutgers The State University of New Jersey

Status

Completed

Conditions

HIV Infections

Treatments

Other: No intervention

Study type

Observational

Funder types

Other

Identifiers

NCT04889521

Pro2020003234(cross-sec)

Details and patient eligibility

About

Cross-sectional study is to explore the impact of painful neuropathy in the feet on function in persons living with HIV (PLHIV).

Full description

The overall goal of this study is to explore the impact of HIV-associated distal sensory polyneuropathy on physical performance, physical activity, and pain pressure threshold.

The aim is to determine if the presence of painful distal sensory polyneuropathy in the feet adversely affects physical performance, physical activity, and pain pressure threshold in PLHIV.

Enrollment

75 patients

Sex

All

Ages

18 to 89 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

diagnosis of HIV infection currently treated with antiretroviral therapy (ART)
cluster of differentiation 4 cell (CD4 cell) count of at least 200 cells/mm3
18-64 years of age
able to read and write in English
means to travel to a study site
Additional inclusion for cohort with painful neuropathy in the feet:
presence of peripheral neuropathy symptoms in feet
average daily self-reported pain in the feet of at least 3/10 on a 0-10 numerical pain scale
pain in the feet present for at least the past 3 months
no changes in medications used to manage pain in the past 4 weeks

Exclusion criteria

current opportunistic infection(s)
cluster of differentiation 4 cell (CD4 cell) count <200 cells/mm3
dementia
uncontrolled psychiatric disorder
wounds or sores on the feet
musculoskeletal or neurological conditions (other than distal sensory neuropathy) that may affect gait
pregnancy