Neurophysiological Characterization of Postherniotomy Pain

Rigshospitalet

Status: Completed

Conditions: Postoperative Pain; Neuropathic Pain; Postherniotomy Pain

Study type: Observational

Funder types: Other

Identifiers

NCT00719368

KF 01267755

Details and patient eligibility

About

Sensory function is different in persistent postherniotomy pain patients than in operated controls, suggesting this to be a neuropathic pain syndrome. By performing quantitative sensory testing, the specific changes in pain patients will be revealed, thereby aiding in designing future treatment trials. MRI scans of the groin regions in pain patients and control patients will be evaluated by senior MRI specialists assessing potential pathology to the region (Mesh, inflammation, edema, funicle etc.) Assessors will be blinded to clinical status, and surgery.

Enrollment: 48 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male patients >18 yrs
• Inguinal herniotomy >1 yr previously
• No sign of hernia recurrence
• Unilateral chronic groin pain lasting more than 3 months
• Moderate/severe pain related impairment of everyday activities.

Exclusion criteria

• Other causes of persistent pain in groin region (hip, other surgical procedures)

Trial design

48 participants in 2 patient groups

pain-free control

Description:

Pain-free controls from previous prospective study (KF 01294867), operated \>2 years previously

Pain Patients

Description:

Patients with persistent postherniotomy pain lasting \>1 year and pain related impaired daily function