Neuropsychiatric Effects of Deep Brain Stimulation in Patients With Parkinson's Disease

University of California San Diego

Status: Completed

Conditions: Parkinson's Disease

Treatments: Procedure: Stimulation of the subthalamic nucleus

Study type: Interventional

Funder types: Other

Identifiers

NCT01306539

HSC-07-4849

Details and patient eligibility

About

Stimulation of the subthalamic nucleus will have effects on various aspects of neuropsychiatric function.

Enrollment: 20 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Participants diagnosed with idiopathic Parkinson's disease that meet criteria for treatment of their disease with STN-DBS. Participants will be selected for this study without regard for age (provided they are older than 18), gender or ethnic background.
• Participants must have undergone subthalamic nucleus DBS surgery and be receiving treatment at the Scripps Clinic in La Jolla, CA

Exclusion criteria

• Patients under 18 years old.
• Patients with mini-mental status scores below 26/30.
• Patients with known psychiatric disease.
• Patients who are too infirm, demented or dysarthric to clearly understand the consenting process, task instructions, or to communicate verbally regarding participation or non-participation.

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Double Blind

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20 participants in 1 patient group

Deep Brain Stimulation

Experimental group

Description:

Parkinson's patients with deep brain stimulation in the subthalamic nucleus.

Treatment:

Procedure: Stimulation of the subthalamic nucleus