Neurorehabilitation on Upper Limb and on Fatigue in Multiple Sclerosis

Don Carlo Gnocchi Onlus Foundation

Status: Unknown

Conditions: Multiple Sclerosis

Treatments: Other: Task Oriented rehabilitation and aerobic training

Study type: Interventional

Funder types: Other

Identifiers

NCT02960984

UL_SM

Details and patient eligibility

About

In Multiple Sclerosis the multiplicity of physical and psychological dysfunctions have been shown to exhibit a number of life-altering problems such as fatigue, limb weakness, alteration of upper extremity fine motor coordination, loss of sensation, spasticity. These problems affect performance of many daily living activities (ADL) such as dressing, bathing, self-care, and writing, thus reducing functional independence and self-rated quality of life.

Twenty people with Multiple Sclerosis will receive neurorehabilitation treatment comprising a combination of aerobic training and upper limb task-oriented training.

The aim of this pilot crossover study is to evaluate the effects of neurorehabilitation on upper limb performance and on fatigue in People with Multiple Sclerosis.

Enrollment: 20 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of Multiple Sclerosis
• no relapses in the last three months
• Expanded Disability Status Scale (EDSS) ≤ 8;

Exclusion criteria

• subjects with relapses
• worsening of the pathology in the last three months
• subjects with cognitive and psychiatric disturbances
• subjects with cardiovascular disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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20 participants in 2 patient groups

Neurorehabilitation

Experimental group

Description:

Participants in the experimental group will receive 1 hour treatment comprising 30' of aerobic training on an ergometer and 30' of task-oriented training focused on uppper limb rehabilitation.

Treatment:

Other: Task Oriented rehabilitation and aerobic training

Baseline

No Intervention group

Description:

No intervention is planned