Neutralizing Antibody Level After COVID-19 Vaccination

Kyungpook National University

Status: Enrolling

Conditions: Covid19

Treatments: Diagnostic Test: COVID-19 neutralizing antibody

Study type: Observational

Funder types: Other

Identifiers

NCT05083026

KNUCH-2021005-001-001

Details and patient eligibility

About

1. serial of neutralizing antibody at 2, 4, 6, 9, 12 month after COVID-19 vaccination
2. investigate the factors on antibody titer.

Full description

1. serial of neutralizing antibody at 2, 4, 6, 9, 12 month after COVID-19 vaccination 1) semi-quantitative measurement of neutralizing antibody at 2, 4, 6, 9, 12 month after COVID-19 vaccination 2) investigate the duration maintaining acceptable range (over 30% inhibition)
2. investigate the factors on antibody titer at 2 month after vaccination 1) potential factors: age, sex, body weight, height, use of medication, use of antipyretics (NSAID or tyrenol), side effect of COVID-19 vaccination 2) correlation between antibody titer and potential factors
3. Compare 4 diagnostic ELISA kit at 2 month after vaccination 1) measure neutralizung antibody using ELISA kits from 4 different companies 2) investigate correlation coefficient of antibody titer between companies

Enrollment: 51 estimated patients

Sex: All

Ages: 20 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• healthcare works after completion of COVID-19 vaccination
• 20-60 years
• sign the agreement of study

Exclusion criteria

• serious underlying diseases