Neutropenic Fever, Inflammatory Markers and Sepsis in Haematological Patients

Kuopio University Hospital

Status: Completed

Conditions: Sepsis

Treatments: Other: Severe sepsis vs. non-severe sepsis

Study type: Observational

Funder types: Other

Identifiers

NCT00781040

KUH5101409

Details and patient eligibility

About

The aim of this study is to find out whether inflammation markers including cardiac markers have predictive value in evaluation of pathogenesis of sepsis in neutropenic haematological patients.

Full description

Adult AML and ASCT patients with neutropenic fever. Observation of possible progress to severe sepsis or septic shock. Blood sample collection on days 0-3 (from the beginning of neutropenic fever).

Enrollment: 273 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• diagnosis: acute myeloid leukaemia
• age under 70 years
• neutropenic fever

Exclusion criteria

• age above 70 years
• no neutropenic fever

Trial design

273 participants in 1 patient group

Neutropenic patients

Description:

Adult AML and ASCT patients with neutropenic fever.

Treatment:

Other: Severe sepsis vs. non-severe sepsis