Neutrophil Phenotypic Profiling and Surgical Site Infections in Surgical Patients

Boston Children's Hospital

Status: Active, not recruiting

Conditions: Surgical Site Infection

Treatments: Other: Surgical Site Infection

Study type: Observational

Funder types: Other

Identifiers

NCT04773457

IRB-P00037804

Details and patient eligibility

About

Surgical site infections (SSIs) are one of the major hospital acquired infections and responsible for the most cost among the hospital acquired infections. The objective of this study is to assess the neutrophil functional profiles and their associations with SSIs.

Enrollment: 220 estimated patients

Sex: All

Ages: 12 months to 19 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• scheduled for an elective open gastrointestinal surgical procedure or spine fusion surgery

Exclusion criteria

• On chronic immunosuppressive drugs such as chronic corticosteroid use
• preexisting immunodeficiency diseases

Trial design

220 participants in 2 patient groups

Spine Surgery

Description:

Pediatric patients presenting for elective spine fusion surgery at Boston Children's Hospital

Treatment:

Other: Surgical Site Infection

Abdominal Surgery

Description:

Pediatric patients presenting for elective abdominal surgery at Boston Children's Hospital

Treatment:

Other: Surgical Site Infection