Neutrophil-to Lymphocyte and Monocyte-to-Lymphocyte Ratios in Exudative Pleural Effusion

Alexandria University

Status: Completed

Conditions: Effusion

Treatments: Procedure: medical thoracoscopy

Study type: Observational

Funder types: Other

Identifiers

NCT07003204

lymphocyte- monocyte- exudate

Details and patient eligibility

About

Exudative pleural effusion (EPE) presents a diagnostic challenge, requiring accurate biomarkers to predict outcomes and guide treatment. The neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) in pleural fluid are emerging as potential prognostic markers. We aimed to assess the diagnostic and prognostic utility of pleural fluid NLR and MLR in EPE.

Full description

Pleural fluid NLR and MLR are reliable biomarkers for diagnosing malignant pleural effusion and predicting poorer survival outcomes. These ratios may be useful in clinical practice, especially in resource-limited settings, to guide decision-making in the management of pleural effusions.

Enrollment: 60 patients

Sex: All

Ages: 18+ months old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult patients aged 18-80 years with an EPE diagnosis confirmed by thoracentesis.

Exclusion criteria

• Exclusion criteria included patients with a history of recent surgery, corticosteroid use, or those with mixed effusion types.

Trial design

60 participants in 1 patient group

only one group of patients

Description:

prospective cohort randomized control study

Treatment:

Procedure: medical thoracoscopy