New Approach for Ovarian PRP Injection for Poor Responders

Bassem Ayman Mahmoud Assaf

Status: Active, not recruiting

Conditions: Poor Responders

Study type: Observational

Funder types: Other

Identifiers

NCT06663930

New Approach For Ovarian PRP

Details and patient eligibility

About

New Approach For Ovarian PRP Injection for poor responders

Full description

Poor ovarian responders are at high risk of unsuccessful IVF/ICSI trials. In the last few years, many studies showed significant improvement of ovarian reserve parameters after PRP injection. There was no consensus regarding the route of injection, the volume injected, the location of PRP injection inside the ovary, the number of injection and the number of the cycle in which PRP is injected.

Enrollment: 21 patients

Sex: Female

Ages: 30 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• AMH : < 0.5 ng/ml
• FSH: > 10 miu but < 25 miu.
• AFC : < 5 in both ovaries
• Poor ovarian response, in a previous IVF/ICSI trial , resulting in 3 or fewer oocytes.
• Normal uterine cavity , demonstrated by a recent hysteroscopy

Exclusion criteria

• Primary ovarian insufficiency with FSH > 25 miu.
• Previous ovarian surgery or Chemotherapy.
• On going Anticoagulant use.
• Carcinomas or a history of chronic pelvic pain.
• Present infection.
• Hemoglobin level lower than 11 g/L
• platelet count lower than 150 x 10³/μL.