New Diabetes Mellitus and Pre-Diabetes With First-time Diagnosed Coronary Artery Disease (DMCAD)

Saud Al Babtain Cardiac Center

Status: Completed

Conditions: Coronary Artery Disease; Diabetes; PreDiabetes

Treatments: Diagnostic Test: Coronary angiography

Study type: Observational

Funder types: Other

Identifiers

NCT05208424

IRB-2020-02

Details and patient eligibility

About

A prospective analytic study to evaluate the incidence, clinical and laboratory characteristics, extent of coronary artery disease and short-term outcome of newly diagnosed diabetes and pre-diabetes in patients with first-time diagnosed coronary artery disease treated in Saud Al Babtain Cardiac Center.

Enrollment: 300 patients

Sex: All

Ages: 18+ months old

Volunteers: No Healthy Volunteers

Inclusion criteria

• First time diagnosed coronary artery disease as confirmed by invasive coronary angiography
• Emergently or electively admitted as coronary artery disease patients.
• Informed consent form

Exclusion criteria

• Prior diagnosis of diabetes or pre-diabetes based on the diagnostic criteria of the American Diabetes Association (ADA, 2020)
• Known coronary artery disease

Trial design

300 participants in 3 patient groups

Normal glycemia

Description:

100 patients without evidence of dysglycemia.

Treatment:

Diagnostic Test: Coronary angiography

Prediabetes

Description:

100 patients with evidence of pre-diabetes defined as hemoglobin A1C (HbA1c) 5.7-6.4% with or without fasting plasma glucose (FPG) of 100 mg/dL to 125 mg/dL.

Treatment:

Diagnostic Test: Coronary angiography

Diabetes

Description:

100 patients without evidence diabetes defined as hemoglobin HbA1c \> 6.4% with or without FPG \>125 mg/dL.

Treatment:

Diagnostic Test: Coronary angiography