New Protocol in Unexplained Infertility

Tanta University

Status and phase: Enrolling; Phase 4

Conditions: Unexplained Infertility

Treatments: Drug: Standard protocol in IUI; Drug: Gonadotropin

Study type: Interventional

Funder types: Other

Identifiers

NCT04754243

ANTIUI

Details and patient eligibility

About

The new protocol ANTIUI provides good results regarding ovulation and pregnancy rates in patients with unexplained infertility

Full description

Patients with unexplained infertility has normal investigations regarding hormonal, structural data. Semen is normal but no pregnancy occurs.

Before trying ICSI, we could help these patients with ANTIUI

Enrollment: 200 estimated patients

Sex: Female

Ages: 20 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Unexplained infertility
• Duration less than 5 years
• Good ovarian reserve AMH> 1.1
• Normal patent tubes
• No previous trials of IUI with the same protocol

Exclusion criteria

• Age > 35 years
• Duration of infertility> 5 years
• Abnormal semen
• Hypoplastic tubes
• prior failed ICSI

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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200 participants in 2 patient groups

Study group

Experimental group

Description:

Will receive ANTIUI protocol

Treatment:

Drug: Gonadotropin

Control group

Active Comparator group

Description:

Will receive standard protocol in IUI and unexplained infertility

Treatment:

Drug: Standard protocol in IUI