Newborn Feeding and Infant Phenotype

Imperial College London

Status: Completed

Conditions: Breast Feeding

Study type: Observational

Funder types: Other

Identifiers

NCT02033005

CRO1461

Details and patient eligibility

About

Breast feeding is believed to be beneficial to long-term health but how these effects are mediated is unknown. I suggest that this may be through effects on body composition and metabolism.

I will compare adipose tissue and liver fat deposition in healthy, full term breast and formula fed infants babies shortly after birth and around 12 weeks.

Enrollment: 124 patients

Sex: All

Ages: Under 4 weeks old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy baby
• Term baby
• Appropriate weight for gestational age (UK - WHO 2009 growth charts)

Exclusion criteria

• Infants of diabetic mothers
• Infants of smokers
• Infants fed non-commercial or non-cows milk based infant formulae

Trial design

124 participants in 3 patient groups

Breastfed infants

Description:

\>80% of feeds consisting of breast milk at both scanning points

Formula-fed infants

Description:

\>80% of feeds consisting of formula milk at both scanning points

Mixed-fed infants

Description:

20%-80% of feeds consisting of breast milk.