NFL Dynamics as a Predictor Factor in Patients With Out of Hospital Cardiac Arrest

University Medical Centre Maribor

Status: Enrolling

Conditions: Out-Of-Hospital Cardiac Arrest; Neurological Injury

Study type: Observational

Funder types: Other

Identifiers

NCT05218278

IRP-2021/01-01

Details and patient eligibility

About

To investigate the pharmacodynamics of light chain of NFL in patients with out-of hospital cardiac arrest after successful resuscitation and determine the difference in the serum levels of NFL in patients with favorable neurological outcome compared to those with non-favorable neurological outcome.

Full description

To investigate the serum levels of the light chain of NFL at different time points after ICU admission (12, 24, 30, 36, 42, 48 hours after ICU admission) patients with out-of hospital cardiac arrest after successful resuscitation and determine the difference in the serum levels of NFL in patients with favorable neurological outcome compared to those with non-favorable neurological outcome.

Enrollment: 60 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• out-of-hospital cardiac arrest successfully resuscitated and admitted to the ICU

Exclusion criteria

• trauma, drowning, electrocution, less than 18 years of age,

Trial design

60 participants in 2 patient groups

Patients with favorable neurlogical outcome

Description:

CPC 1/2

Patients with non-favorable neurological outcome

Description:

CPC3-5