NGAL Predictive Value of Acute Kidney Failure After Cardiac Surgery in Patients With Preoperative Chronic Kidney Failure (NGAL-CKF)

Hopital Jean Minjoz

Status: Unknown

Conditions: Cardiac Surgical Procedures; Postoperative KIDNEY FAILURE, ACUTE; Preoperative KIDNEY FAILURE, CHRONIC

Study type: Observational

Funder types: Other

Identifiers

NCT01227122

2010-A00111-38

Details and patient eligibility

About

Primary endpoint: To evaluate predictive value of plasmatic levels of Neutrophil Gelatinase Associated Lipocalin (NGAL) to reveal acute kidney failure after cardiac surgery in patients with preoperative chronic kidney failure Secondary endpoint is to obtain threshold values of NGAL.

Full description

(N/A)

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Renal clearance less than 60 mL/min
• Able to give written consent
• Elective valve surgery
• Elective CABG surgery

Exclusion criteria

• Less than 18 years old
• Iodine injection within 3 days before surgery
• Iodine injection within 24 first postoperative hours
• preoperative infection
• evolutive cancer disease
• Refusal
• Pregnancy
• Unable to give written consent