Nicotine and Cannabis Vape Labeling Experiment - Spring 2025 (EPIC/ADVANCE)
Status
Invitation-only
Conditions
Nicotine
Electronic Cigarette Use
Cannabis
Adolescent
Vaping
Treatments
Other: Vaping Device Labeling
Study type
Interventional
Funder types
Other
NIH
Identifiers
NCT06919276
5R01CA229617-06 (U.S. NIH Grant/Contract)
5U54CA180905-12 (U.S. NIH Grant/Contract)
5K24DA048160 (U.S. NIH Grant/Contract)
UP-23-00483/HS-19-00682
Details and patient eligibility
About
This study assesses how the ways in which nicotine and cannabis vaping devices are labeled impact use susceptibility, anticipated effects, and health harm.
Full description
The primary objectives of the study: (1) Determine whether different device labels with the contained substance (nicotine or cannabis) affect adolescent use susceptibility, anticipated effects or impairment, and perceived health harms; (2) Determine whether device color/product flavor differentially impact the study outcomes.
Enrollment
3,900 estimated patients
Sex
All
Ages
11 to 19 years old
Volunteers
Accepts Healthy Volunteers
Inclusion criteria
- Participants must be enrolled in a partnering high school.
Exclusion criteria
- Participants who cannot independently understand study consent and the study surveys are ineligible.
Trial design
Primary purpose
Other
Allocation
Randomized
Interventional model
Parallel Assignment
Masking
Single Blind
3,900 participants in 21 patient groups
Mint - Labeling Condition 1
Experimental group
Description:
Participants will view an image of a mint-colored and flavored vape with label condition 1.
Treatment:
Other: Vaping Device Labeling
Mint - Labeling Condition 2
Experimental group
Description:
Participants will view an image of a mint-colored and flavored vape with label condition 2.
Treatment:
Other: Vaping Device Labeling
Mint - Labeling Condition 3
Experimental group
Description:
Participants will view an image of a mint-colored and flavored vape with label condition 3.
Treatment:
Other: Vaping Device Labeling
Mint - Labeling Condition 4
Experimental group
Description:
Participants will view an image of a mint-colored and flavored vape with label condition 4.
Treatment:
Other: Vaping Device Labeling
Mint - Labeling Condition 5
Experimental group
Description:
Participants will view an image of a mint-colored and flavored vape with label condition 5.
Treatment:
Other: Vaping Device Labeling
Mint - Labeling Condition 6
Experimental group
Description:
Participants will view an image of a mint-colored and flavored vape with label condition 6.
Treatment:
Other: Vaping Device Labeling
Mint - Labeling Condition 7
Experimental group
Description:
Participants will view an image of a mint-colored and flavored vape with label condition 7.
Treatment:
Other: Vaping Device Labeling
Original - Labeling Condition 1
Experimental group
Description:
Participants will view an image of a white colored and original vape with label condition 1.
Treatment:
Other: Vaping Device Labeling
Original - Labeling Condition 2
Experimental group
Description:
Participants will view an image of a white colored and original vape with label condition 2.
Treatment:
Other: Vaping Device Labeling
Original - Labeling Condition 3
Experimental group
Description:
Participants will view an image of a white colored and original vape with label condition 3.
Treatment:
Other: Vaping Device Labeling
Original - Labeling Condition 4
Experimental group
Description:
Participants will view an image of a white colored and original vape with label condition 4.
Treatment:
Other: Vaping Device Labeling
Original - Labeling Condition 5
Experimental group
Description:
Participants will view an image of a white colored and original vape with label condition 5.
Treatment:
Other: Vaping Device Labeling
Original - Labeling Condition 6
Experimental group
Description:
Participants will view an image of a white colored and original vape with label condition 6.
Treatment:
Other: Vaping Device Labeling
Original - Labeling Condition 7
Experimental group
Description:
Participants will view an image of a white colored and original vape with label condition 7.
Treatment:
Other: Vaping Device Labeling
Blueberry - Labeling Condition 1
Experimental group
Description:
Participants will view an image of a blue-colored and blueberry flavored vape with label condition 1.
Treatment:
Other: Vaping Device Labeling
Blueberry - Labeling Condition 2
Experimental group
Description:
Participants will view an image of a blue-colored and blueberry flavored vape with label condition 2.
Treatment:
Other: Vaping Device Labeling
Blueberry - Labeling Condition 3
Experimental group
Description:
Participants will view an image of a blue-colored and blueberry flavored vape with label condition 3.
Treatment:
Other: Vaping Device Labeling
Blueberry - Labeling Condition 4
Experimental group
Description:
Participants will view an image of a blue-colored and blueberry flavored vape with label condition 4.
Treatment:
Other: Vaping Device Labeling
Blueberry - Labeling Condition 5
Experimental group
Description:
Participants will view an image of a blue-colored and blueberry flavored vape with label condition 5.
Treatment:
Other: Vaping Device Labeling
Blueberry - Labeling Condition 6
Experimental group
Description:
Participants will view an image of a blue-colored and blueberry flavored vape with label condition 6.
Treatment:
Other: Vaping Device Labeling
Blueberry - Labeling Condition 7
Experimental group
Description:
Participants will view an image of a blue-colored and blueberry flavored vape with label condition 1.
Treatment:
Other: Vaping Device Labeling
Trial contacts and locations
1
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Data sourced from clinicaltrials.gov
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