Nigella Sativa Oil Extract and Xenograft Bone Graft in Treatment of Infra-bony Defects

Tanta University

Status and phase

Unknown

Phase 2

Conditions

Localized Aggressive Periodontitis

Treatments

Procedure: periodontal regenerative surgery

Study type

Interventional

Funder types

Other

Identifiers

NCT04722380

Details and patient eligibility

About

The aim of this study will be to evaluate, clinically, and radiographically the effect of Nigella Sativa oil extract Mixed with xenograft versus xenograft alone in the treatment of intra-bony defects in patients with aggressive periodontitis.

Full description

in 10 patients, twenty sites in subjects with, localized aggressive periodontitis, with CAL ≥ 5 will be included in the present study. Sites will be allocated randomly to be surgically treated with, Nigella Sativa oil extract Mixed with xenograft or xenograft alone. At baseline, 3, 6 after surgery, the following clinical parameters (PD, CAL, BOP) and CBCT at baseline and 6 months x-ray will be recorded.

Enrollment

10 estimated patients

Sex

All

Ages

18 to 30 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

systemically healthy patients were selected
- patients who had not received any medications for the previous six months that may interfere with periodontal tissue health or healing.
- Patients should demonstrate their ability to maintain good oral hygiene

Exclusion criteria

• Smokers and pregnant patients.
- Medically compromised patients and systemic conditions precluding periodontal surgery.
- Subjects who do not comply with oral hygiene measures as evidenced in recall visits.
- Restoration or caries in the site to be treated or non-vital tooth
- Restoration or caries in the site to be treated or non-vital tooth