Nighttime Protein Intake on Overnight Lipolysis and Morning Fat Oxidation in Obese Men
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About
Single macronutrients will be consumed before sleep by obese men. Overnight lipolysis will be measured with the microdialysis technique by measuring glycerol concentration and blood flow in abdominal adipose tissue. Morning fat oxidation will be measured with indirect calorimetry.
The investigators hypothesize that carbohydrate intake will blunt the overnight lipolysis rate compared to casein protein and a non-caloric placebo. The investigators also hypothesize that casein and placebo will not be significantly different from each other in terms of overnight lipolysis.
Enrollment
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Inclusion criteria
- Healthy, sedentary overweight or obese (BMI ≥25 kg/m^2; body fat ≥ 25% ) men
Exclusion criteria
- Men that have been exercising for more than 2 days per week for more than 45 minutes per session (within the past 6 months), have uncontrolled hypertension (Blood Pressure (BP)>160/100 mmHg, diagnosed cardiovascular disease, stroke, diabetes, thyroid or kidney dysfunction, take cholesterol medication, or have any allergies to milk products will be excluded. Smokers will also be excluded.
Trial design
Primary purpose
Allocation
Interventional model
Masking
12 participants in 2 patient groups, including a placebo group
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Data sourced from clinicaltrials.gov
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