NMES During the Day and Prior to Sleep (ESPRO2)

Maastricht University Medical Centre (MUMC)

Status

Completed

Conditions

Sarcopenia

Treatments

Procedure: Dietary protein plus NMES during the day

Procedure: Dietary protein plus NMES prior to sleep

Study type

Interventional

Funder types

Other

Identifiers

NCT02253329

MEC 14-3-042

Details and patient eligibility

About

In the present study, the effect of a bolus of intrinsically labeled milk directly after one-legged NMES (Neuromuscular Electrical Stimulation) will be studied under two conditions: during the day and prior to sleep

Full description

In the present study, the effect of a bolus of intrinsically labeled milk directly after an hour of one-legged NMES (Neuromuscular Electrical Stimulation) will be studied under two conditions: during the day and immediately prior to sleep

Enrollment

16 patients

Sex

Male

Ages

65 to 85 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Age 65-85 years
Male
18.5 ≤ BMI ≤ 30.0

Exclusion criteria

Type II diabetes
All co morbidities interacting with mobility and muscle metabolism of the lower limbs (e.g. arthrosis, arthritis, spasticity/rigidity, all neurological disorders, paralysis, hip/knee surgery).
Use of anticoagulants, blood diseases, allergy for lidocaine
Use of NSAIDs (non-steroidal anti-inflammatory drugs) and acetylsalicylic acid
Patients suffering from PKU (Phenylketonuria)
Presence of implantable cardioverter defibrillator and/or pacemaker
Performed regular resistance type exercise in the past 6 months
Use of any tools to assist during walking (cane/ crutches/ walker)
(Partial) foot/ leg amputation