Noise, Oxidative Stress and Cardiovascular System (NOXYCARD)

University of Belgrade

Status: Not yet enrolling

Conditions: Noise; Adverse Effect; Noise Exposure

Treatments: Other: Exposure to loud pre-recorded road traffic noise

Study type: Observational

Funder types: Other

Identifiers

NCT06294340

1322-IX/42

Details and patient eligibility

About

Environmental noise represents a health problem for at least one in five citizens of the European Union. Noise exposure leads to the development of arterial hypertension, myocardial infarction, stroke, and obesity. Given the limited information on noise exposure and noise effects on humans in the Republic of Serbia, the overall objective of NOXYCARD is to collect environmental noise levels data; to identify long-term and short-term noise effects on the cardiovascular system; and to evaluate the levels of blood stress hormones, oxidative stress, and inflammation in individuals with normal body weight and individuals with obesity.

Enrollment: 150 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age 18-65
• both genders
• good self-reported health

Exclusion criteria

• diabetes mellitus
• arterial hypertension or other cardiovascular diseases
• kidney diseases
• pregnancy
• malignant diseases
• mental diseases

Trial design

150 participants in 2 patient groups

Participants with normal body weight

Description:

The effects of noise exposure on blood pressure, cardiovascular and hemodynamic parameters, stress hormones, and markers of oxidative stress and inflammation in individuals with normal body weight.

Treatment:

Other: Exposure to loud pre-recorded road traffic noise

Overweight / obese participants

Description:

The effects of noise exposure on blood pressure, cardiovascular and hemodynamic parameters, stress hormones, and markers of oxidative stress and inflammation in individuals with overweight/obesity.

Treatment:

Other: Exposure to loud pre-recorded road traffic noise