Non Alcoholic Fatty Liver Disease Influence of Statin Therapy

Shaare Zedek Medical Center

Status

Withdrawn

Conditions

Non-alcoholic Fatty Liver Disease (NAFLD)

Treatments

Procedure: Ultrasound to demonstrate existence of fatty liver

Study type

Interventional

Funder types

Other

Identifiers

NCT00375349

20173CTIL

Details and patient eligibility

About

Aim:

To determine the prevalence of fatty liver in a cohort of patients hospitalized with chest pain in the Cardiology department.
To assess the effect of statins on the prevalence of fatty liver by a cross sectional survey of patients hospitalized with chest pain.

Full description

Consecutive patients hospitalized with chest pain will be recruited at the cardiology department. Patients with an inflammatory condition, recent infection or history of alcoholism will be excluded. After signing an informed consent each patient will undergo an ultrasound examination for diagnosis of fatty liver. Information regarding BMI, hypertension and use of medications will be collected on each patient. Blood samples for fasting glucose, hemoglobin A1C, lipid profile, ESR, and CRP and liver function tests will be collected from each participant. Prevalence of fatty liver in patients who have been taking statins for 6 months or more statins will be compared to patients who have been taking statins for a lesser period and to those who do have not taken statins using a multivariate regression analysis.

Serum samples will be frozen and kept for future ongoing research.

Sex

All

Ages

18 to 85 years old

Volunteers

No Healthy Volunteers

Inclusion criteria