Non-Center Involving Diabetic Macular Edema Progression in Early Postoperative Period After Phacoemulsification

Ain Shams University

Status: Enrolling

Conditions: Diabetic Macular Edema; Phacoemulsification; Non-Center

Treatments: Other: Fluorescein angiography; Other: Coloured photography; Other: Optical coherence tomography

Study type: Observational

Funder types: Other

Identifiers

NCT07038967

FMASU R127/2025

Details and patient eligibility

About

This study aims to evaluate the progression of non-center-involving diabetic macular edema in the early postoperative period following phacoemulsification.

Full description

Diabetic patients have been reported to have a higher prevalence of cataract and develop it at an earlier age compared with nondiabetic individuals.

According to recent population-based studies, diabetic macular edema (DME) is the most common cause of vision loss, with the incidence of non-center-involving DME (NCIDME) being higher than that of center-involving DME (CIDME). The prevalence of NCIDME in an urban south Indian population is 10.8%.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥18 years.
• Both sexes.
• Patients with Grade I - Grade II nuclear cataract and non-center-involving diabetic macular edema (NCIDME).

Exclusion criteria

• Traumatic cataract.
• Severe Non-Proliferative/ Proliferative Diabetic Retinopathy.
• Marked Asymmetry of retinopathy between both eyes.
• Mature senile cataract or severe lens opacity.
• Potentiality to have Phacotrabeculectomy surgery.
• Complications during or after the surgery.

Trial design

50 participants in 1 patient group

Study group

Description:

Patients with Grade I - Grade II nuclear cataract and non-center-involving diabetic macular edema (NCIDME)

Treatment:

Other: Optical coherence tomography

Other: Coloured photography

Other: Fluorescein angiography