NON-COlorectal Liver METastases Undergoing Liver Resection (NONCOLMET)

University Hospital Maggiore della Carità of Novara

Status: Not yet enrolling

Conditions: Liver Metastases

Treatments: Procedure: liver resection

Study type: Observational

Funder types: Other

Identifiers

NCT06542926

NONCOLMET01

Details and patient eligibility

About

Liver metastases (LM) are common in various types of malignant diseases, either at the diagnosis of the primary tumour or at a later time point. While the resection of colorectal LM (CRLM) is a well-established procedure, with survival rates superior to chemotherapy alone, controversial data still exist on liver resection for non-colorectal LM (NCRLM) (2, 3). These patients comprise a diverse and heterogeneous group usually excluded from surgery due to advanced tumour stage or the presence of concomitant extrahepatic disease. To date, no randomized clinical trial on the surgical treatment of NCRLM has been conducted, and only few retrospective reports are available.The scope of this research project is to develop a large registry of patients undergoing liver surgery for non-colorectal liver metastases.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria:

• Signature informed consent
• Age ≥ 18 years
• Histologically confirmed diagnosis of NCRLM (first diagnosis or relapse)
• Liver resection performed.

Exclusion criteria

• ASA IV
• Severe psychiatric pathology
• Unable to follow a clinical examination pattern during observation.
• Patient submitted exclusively to interventional locoregional procedures other than liver resection.