Non-Helium Magnetoencephalography in Autism Spectrum Disorder

Guangzhou Women and Children's Medical Center

Status

Enrolling

Conditions

Autism Spectrum Disorder (ASD)

Treatments

Diagnostic Test: Magnetoencephalography

Study type

Observational

Funder types

Other

Identifiers

NCT07064967

447A01

Details and patient eligibility

About

The goal of this observational study is to learn how brain activity in children with autism spectrum disorder (ASD) differs from typical developing children using magnetoencephalography (MEG).

The main questions this study aims to answer are:

Do children with ASD show different patterns of neural oscillation compared to typically developing children? Can MEG identify specific brain features that help ASD diagnosis?

Participants will undergo MEG scan in both resting and tasking state, and their brain activity will be analyzed for characteristic neural oscillations and connectivity patterns.

This study may help develop better tools for early ASD diagnosis.

Enrollment

80 estimated patients

Sex

Male

Ages

6 to 12 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Boys aged 6 to 12 years;
Diagnosis of Autism Spectrum Disorder meeting DSM-5 criteria;
Intelligence quotient (IQ) score > 70 (assessed via Wechsler Intelligence Scale for Children or other validated cognitive test);
Sufficient compliance to participate in MEG experiments.

Exclusion criteria

Comorbid neurological disorders, genetic syndromes, or severe developmental disabilities;
Metallic implants that may interfere with MEG signal acquisition;
Current use of antipsychotic medications or sedatives.