Non-Helium Magnetoencephalography in Pediatric Brain Tumors

Guangzhou Women and Children's Medical Center

Status: Enrolling

Conditions: Pediatric Brain Tumor

Treatments: Diagnostic Test: Magnetoencephalography plus Computed Tomography/Magnetic Resonance Imaging

Study type: Observational

Funder types: Other

Identifiers

NCT06943742

449A01

Details and patient eligibility

About

This observational study aims to evaluate the effectiveness of magnetoencephalography (MEG) in the preoperative assessment of pediatric brain tumors, particularly in determining the extent of resection, and compare it with computed tomography (CT) and magnetic resonance imaging (MRI).

The main questions this study aims to answer are:

What is the consistency between MEG and CT/MRI in localizing pediatric brain tumors? What is the clinical efficacy of MEG in determining the extent of resection of pediatric brain tumors preoperatively?

Participants will:

Undergo both MEG and CT/MRI examinations for preoperative assessment, and the extent of tumor resection will be determined by the comprehensive results of the above examinations.

Be followed up with MEG and CT/MRI at 1, 3, and 6 months after surgery, along with neurological and quality-of-life assessments.

Enrollment: 100 estimated patients

Sex: All

Ages: 3 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age range: 3-18 years old;
• Clinically diagnosed with brain tumor;
• Capable of cooperating with magnetoencephalography evaluation and recording.

Exclusion criteria

• Patients with serious comorbidities or neurological or psychiatric disorders that affect magnetoencephalography examination.
• Patients using drugs that affect central nervous system function;
• Patients who are not suitable for surgical procedures;
• Patients with progressive neurological disorders.