Non-Invasive Brain Stimulation

The Chinese University of Hong Kong

Status: Unknown

Conditions: Stroke

Treatments: Device: Transcranial Direct Current Stimulator

Study type: Interventional

Funder types: Other

Identifiers

NCT04318522

2017.331

Details and patient eligibility

About

The study focusses on utilizing neuroimaging modalities, including Electroencephalography (EEG) and Functional Magnetic Resonance Imaging (fMRI) to study the impact of non-invasive brain stimulation on the prefrontal cortex during a cognitive task.

Full description

In this study, a total of 40 subjects will be randomly assigned to 2 groups i.e. experimental and sham. Conventional transcranial direct current stimulation (c-tDCS) and high-definition transcranial direct current stimulation (HD-tDCS) will be used to stimulate the prefrontal cortex of the brain. EEG and fMRI will be collected before, during and after stimulation to understand the impact of stimulation on brain dynamics. The investigators hypothesize that the stimulation of the prefrontal cortex will improve performance during cognitive tasks along with changes in the neural processing detected by neuroimaging modalities.

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Right Handedness,
• Age > 18

Exclusion criteria

• History of any other neurological disease,
• Any psychological or psychiatric disease,
• Significant visual or auditory impairments,
• tDCS contraindications including implanted metallic or electronic devices, seizures or convulsions, and pregnancy.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

Stimulation Group

Experimental group

Treatment:

Device: Transcranial Direct Current Stimulator

Control Group

Sham Comparator group

Treatment:

Device: Transcranial Direct Current Stimulator