Non-invasive Brain Stimulation for Auditory Verbal Hallucinations in Schizophrenia

Charité University Medicine Berlin

Status: Completed

Conditions: Auditory Verbal Hallucinations; Schizophrenia

Treatments: Device: tDCS

Study type: Interventional

Funder types: Other

Identifiers

NCT01801787

EA4/123/12

Details and patient eligibility

About

The current study investigates the basic principles that underlie the efficacy of transcranial direct current stimulation for chronic auditory verbal hallucinations in schizophrenia in a multimodal design.

Enrollment: 30 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• diagnosis of schizophrenia
• chronic auditory verbal hallucinations
• right-handed

Exclusion criteria

• drug abuse other than nicotine
• severe cognitive deficits
• severe medical conditions
• severe neurological disorders
• severe microangiopathy
• history of electroconvulsive therapy
• pregnancy or lactation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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30 participants in 2 patient groups

verum tDCS

Experimental group

Description:

left-hemispheric tDCS: anode placed midway between F3 and FP1, cathode placed midway between T3 and P3

Treatment:

Device: tDCS

sham tDCS

Sham Comparator group

Description:

left-hemispheric sham tDCS: anode placed midway between F3 and FP1, cathode placed midway between T3 and P3

Treatment:

Device: tDCS