Non-Invasive Brain Stimulation to Control Large-Scale Brain Networks

University of Minnesota (UMN)

Status: Completed

Conditions: Working Memory

Treatments: Device: Transcranial alternating current stimulation

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT04680481

STUDY00004009

RF1MH124909 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This project will assess the feasibility of traveling wave transcranial alternating current stimulation (tACS) to modify working memory performance and large-scale brain connectivity in surgical epilepsy patients.

Enrollment: 9 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. the patient can consent for themselves;
2. the patient has or is scheduled for surgically implanted electrodes for the purposes of phase II epilepsy surgical evaluation;
3. age 18+ years old;

Exclusion criteria

1. diminished capacity to consent;

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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9 participants in 2 patient groups

Stimulation Theta Group

Experimental group

Description:

Participants will experience traveling wave transcranial alternating current stimulation over the fronto-parietal regions at 4 Hz (theta condition).

Treatment:

Device: Transcranial alternating current stimulation

Stimulation Beta Group

Experimental group

Description:

Participants will experience traveling wave transcranial alternating current stimulation over the fronto-parietal regions at 23 Hz (beta condition).

Treatment:

Device: Transcranial alternating current stimulation