Non-invasive Evaluation Program for TIPS and Follow Up Network (NEPTUN)

University Hospital Bonn (UKB)

Status: Completed

Conditions: Portal Hypertension

Study type: Observational

Funder types: Other

Identifiers

NCT03628807

NEPTUN

Details and patient eligibility

About

Evaluation of non-invasive prognostic parameters in patients receiving transjugular intrahepatic portosystemic shunt (TIPS) for complications of portal hypertension. Patients are cared according to the local standardized follow up program. Clinical and laboratory data from standard patient care are evaluated for potential prognostic value.

Full description

NEPTUN consists of liver cirrhosis receiving transjugular intrahepatic portosystemic shunt (TIPS) at the Department of Internal Medicine I, University of Bonn, Germany and receiving a structured routine evaluation and follow up program. The diagnosis of cirrhosis was based on clinical, hemodynamic and biochemical parameters, and ultrasound and/or biopsy criteria.

Enrollment: 747 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Insertion of TIPS according to guidelines

Exclusion criteria

• Contraindication for TIPS

Trial design

747 participants in 3 patient groups

Retrospective 1

Description:

Retrospective Bare Metal Stent Cohort that received TIPS from 01/01/1996 to 12/31/2003.

Retrospective 2

Description:

Retrospective Covered Stent Cohort that received TIPS from 01/01/2004 to 12/31/2012.

Prospective

Description:

Prospective cohort that received TIPS from 01/01/2013 onwards