Non Invasive Measurement of Cardiac Index by Impedance Cardiography

Medical University of Graz

Status: Completed

Conditions: Pulmonary Hypertension

Treatments: Other: Impedance cardiography

Study type: Interventional

Funder types: Other

Identifiers

NCT01607515

24-205 ex 11/12

Details and patient eligibility

About

Pulmonary hypertension (PH) is defined as a pulmonary arterial mean pressure (meanPAP) ≥ 25 mmHg in the right heart catheterization.

There are different forms of PH defined in the classification of Dana Point 2008.

PH is diagnosed with right heart catheterization but there are other non invasive methods which can be used for screening like echocardiography, stress echocardiography and cardio pulmonary exercise testing.

For prognosis of PH patients the limitation of the pulmonary circulation is very important. Therefore the cardiac index (CI) is a good parameter for the right ventricular function. The gold standard for CI measures is the thermodilution, an invasive method performed during right heart catheterization.

Full description

In this study the investigators want to evaluate the impedance cardiography (ICG) as a non invasive method for CI measurement. An alternating current of max 400µA and 45 kHz is conducted through the body. The way of the smallest resistance is the blood in the aorta. The impedance changes with the pulsatile blood flow. Out of the Impedance change there can be calculated the CI.

Enrollment: 89 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients who have right heart catheterization written informed consent

Exclusion criteria

• patients who don't have right heart catheterization no written informed consent

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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89 participants in 1 patient group

suspected PH

Other group

Description:

Patients who undergo right heart catheterization for PH diagnosis undergo impedance cardiography

Treatment:

Other: Impedance cardiography